The prognostic value of increasing of high-sensitivity C-reactive protein in chronic heart failure with a preserved ejection fraction. A clinical case

We present a clinical case of a 70-year-old man with a long history of chronic heart failure with preserved ejection fraction (HFpEF), treated for decompensated HFpEF, who developed a fatal ischemic stroke during the first year from the initial hospitalization. The reason for the patient's initial hospitalization in the intensive care unit was decompensation of HFpEF; on the first day, the level of high-sensitivity C-reactive protein in the blood serum was 7.53 mg/l. During the hospitalization, conservative drug therapy was carried out, the patient was discharged in satisfactory condition, and treatment recommendations were given in accordance with current clinical guidelines. 360 days after discharge, the patient was readmitted to the hospital in the intensive care unit due to acute ischemic stroke in the left middle cerebral artery, cerebral edema, and dislocation syndrome. A day later the patient's death was recorded. Using this clinical case as an example, the article discusses the issue of high-sensitivity C-reactive protein levels as a predictor of an increased risk of adverse outcomes in patients with HFpEF.