Clinical and Genomic Characterization of Secondary Rectal Cancer After Radiotherapy for Prostate Cancer
In this case-control study, patients with SRC after RT for PC had worse survival and different molecular profiles than patients with PRC. These findings may help improve the clinical management of SRC.
Authors
- Garrett M. Nash (ORCID: https://orcid.org/0000-0001-9833-2625)
- Julio García‐Aguilar (ORCID: https://orcid.org/0000-0003-2451-0948)
- Henry S. Walch (ORCID: https://orcid.org/0000-0003-1188-350X)
- Floris S. Verheij (ORCID: https://orcid.org/0000-0001-7834-7336)
- Martin R. Weiser (ORCID: https://orcid.org/0000-0002-9577-7984)
- Christina I. Lee
- Anisha Luthra (ORCID: https://orcid.org/0000-0001-9007-3462)
- Chin‐Tung Chen (ORCID: https://orcid.org/0000-0002-3887-6070)
- Walid K. Chatila (ORCID: https://orcid.org/0000-0001-5474-218X)
- Francisco Sánchez-Vega (ORCID: https://orcid.org/0000-0002-2990-4893)
- Maria Widmar (ORCID: https://orcid.org/0000-0002-1145-8370)
- Janet Alvarez (ORCID: https://orcid.org/0000-0001-7853-959X)
- Roni Rosen (ORCID: https://orcid.org/0000-0003-2402-7622)
- Canan Fırat (ORCID: https://orcid.org/0000-0002-4731-1303)
- Dana M. Omer (ORCID: https://orcid.org/0000-0002-2259-2540)
- Georgios Karagkounis (ORCID: https://orcid.org/0000-0003-0759-8108)
- Paul Bernard Romesser (ORCID: https://orcid.org/0000-0001-8268-2903)
- J. Joshua Smith (ORCID: https://orcid.org/0000-0003-2538-5456)
- Iris H. Wei (ORCID: https://orcid.org/0000-0001-9006-9105)
- Emmanouil P. Pappou (ORCID: https://orcid.org/0000-0002-8735-1852)
- Jinru Shia (ORCID: https://orcid.org/0000-0002-4351-2511)
- Philip B. Paty (ORCID: https://orcid.org/0000-0002-7045-2112)
- Hannah Williams (ORCID: https://orcid.org/0000-0001-8928-4190)
- Farheen Shah
Institutions
- Memorial Sloan Kettering Cancer Center (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.1039
- Citations
- 1
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- National Cancer Institute