Study on DNA Damage Gene in Spermatogonial Stem Cells from Idiopathic Nonobstructive Azoospermia: A Bioinformatics Investigation Based on scRNA-seq Data
Our results revealed predictable mechanisms of testicular micro-environment and DNA damage in the regulation of human SSCs and propose potential therapeutic targets for male infertility. Subsequently, further research to confirm the predicted potential mechanisms, pathways, and therapeutic targets should be conducted.
Authors
- Jun Xiang (ORCID: https://orcid.org/0000-0002-1840-4578)
- Yanqiu Wang (ORCID: https://orcid.org/0000-0001-9340-970X)
- Yi Wang (ORCID: https://orcid.org/0000-0002-0192-3195)
- Wei Dong Le
- Yiming Weng
Institutions
- Jiangsu University (CN)
- Tongji University (CN)
- Yixing People's Hospital (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- Cytogenetic and Genome Research
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1159/000545275
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00