Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla

Simvastatin enhances osteogenic differentiation in SCAPs, potentially via TGF-β signalling, implicating its potential role as an adjunctive molecule in dental pulp healing and regeneration in vital pulp treatment approaches.

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Publication Details

Journal
BMC Oral Health
Published
2025-03-18
DOI
https://doi.org/10.1186/s12903-025-05721-z
Citations
4
Primary Topic
Phytochemicals and Medicinal Plants
Type
article
Field-Weighted Citation Impact
9.53
Controls
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article

Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla

Chatvadee Kornsuthisopon, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Thanaphum Noom Osathanon et al.
4 citations
BMC Oral Health
Phytochemicals and Medicinal Plants
9.53
article

Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla

Chatvadee Kornsuthisopon, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Thanaphum Noom Osathanon, Paak Rewthamrongsris, Lakshman P. Samaranayake, Prim Janjarussakul
article en
4 citations

Abstract

Simvastatin enhances osteogenic differentiation in SCAPs, potentially via TGF-β signalling, implicating its potential role as an adjunctive molecule in dental pulp healing and regeneration in vital pulp treatment approaches.

BMC Oral HealthVol. 25(1)
Chulalongkorn University (TH), University of Hong Kong (HK)
Zero hunger
Openalex Percentile: Top 3%
Phytochemicals and Medicinal Plants
9.53
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