Exosomes From Adipose-Derived Stem Cells Inhibit Skin T-Cell Activation and Alleviate Wound Inflammation
ADSCs-exo inhibited PMA-induced skin T-cell activation and inflammatory cytokine expression. Although acute trauma increased DETC expression at the wound site, ADSCs-exo inhibited early DETC and IL-17A expression, preventing excessive inflammation.
Authors
- Boyuan Ren
- Minliang Chen (ORCID: https://orcid.org/0000-0002-6413-5786)
- Hongfan Ding (ORCID: https://orcid.org/0000-0001-5165-0298)
- Qiang Li (ORCID: https://orcid.org/0000-0002-1990-8233)
- Ran Bai (ORCID: https://orcid.org/0000-0002-9107-3381)
- Jide Jin
- Yichen Wang (ORCID: https://orcid.org/0009-0009-9215-0463)
Institutions
- Chinese PLA General Hospital (CN)
- Burn Institute (US)
- Beijing Radiation Center (CN)
Publication Details
- Journal
- Aesthetic Surgery Journal
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1093/asj/sjaf040
- Citations
- 6
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 4.84