Estimated Efficacy of TAK-003 Against Asymptomatic Dengue Infection in Children and Adolescents Participating in the DEN-301 Trial in Asia Pacific and Latin America

The variability in VE algorithms indicates challenges in accurately assessing VE against asymptomatic infections. TAK-003 had a modest impact on asymptomatic dengue infections in the first months postvaccination, mainly in participants with baseline seropositivity.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-03-18
DOI
https://doi.org/10.1093/infdis/jiaf145
Citations
7
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
13.15
Controls
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article

Estimated Efficacy of TAK-003 Against Asymptomatic Dengue Infection in Children and Adolescents Participating in the DEN-301 Trial in Asia Pacific and Latin America

Ivo Sonderegger, Ana Lúcia Lyrio de Oliveira, Shibadas Biswal, Edson Duarte Moreira et al.
7 citations
The Journal of Infectious Diseases
Mosquito-borne diseases and control
13.15
article

Estimated Efficacy of TAK-003 Against Asymptomatic Dengue Infection in Children and Adolescents Participating in the DEN-301 Trial in Asia Pacific and Latin America

Ivo Sonderegger, Ana Lúcia Lyrio de Oliveira, Shibadas Biswal, Edson Duarte Moreira, Vianney Tricou, Maria Theresa Alera, Reynaldo Dietze, Lulu Bravo, Veerachai Watanaveeradej, Nicolas Folschweiller, Yuan Zhao, Tarek El Hindi
article en
7 citations

Abstract

The variability in VE algorithms indicates challenges in accurately assessing VE against asymptomatic infections. TAK-003 had a modest impact on asymptomatic dengue infections in the first months postvaccination, mainly in participants with baseline seropositivity.

The Journal of Infectious DiseasesVol. 231(6)
Institute of Rural Management Anand (IN), University of Alabama at Birmingham (US), Takeda (Switzerland) (CH), Phramongkutklao Hospital (TH), Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória (BR), Armed Forces Research Institute of Medical Science (TH), Takeda (United States) (US), Global Vaccines (United States) (US), Takeda (Japan) (JP), Fundação Oswaldo Cruz (BR), University of the Philippines Manila (PH)
Good health and well-being
Openalex Percentile: Top 1%
Mosquito-borne diseases and control
13.15
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Estimated Efficacy of TAK-003 Against Asymptomatic Dengue Infection in Children and Adolescents Participating in the DEN-301 Trial in Asia Pacific and Latin America — Ivo Sonderegger, Ana Lúcia Lyrio de Oliveira, et al. · The Journal of Infectious Diseases (2025) | TGRS Research Map | TGRS