Hindlimb Unloading Reversibly Attenuates Osteogenic Potential of Rat Skeletal Stem and Progenitor Cells ex vivo
HU leads to inhibition of the osteoplastic function of SSPCs. The presented data are significant for the elucidation of microgravity-induced mechanisms of bone impairment and for the development of countermeasures for astronauts as well as for osteo-deficient patients after prolonged immobilization.
Authors
- Е. Р. Андреева (ORCID: https://orcid.org/0000-0002-1000-5804)
- E. A. Markina (ORCID: https://orcid.org/0000-0003-0631-9082)
- Л. Б. Буравкова (ORCID: https://orcid.org/0000-0001-6994-557X)
Institutions
- Institute of Biomedical Problems (RU)
Publication Details
- Journal
- Cells Tissues Organs
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1159/000545284
- Primary Topic
- Spaceflight effects on biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00