Cross-reactivity of rPvs48/45, a recombinant Plasmodium vivax protein, with plasma from Plasmodium falciparum endemic areas of Africa
Plasma from African volunteers predominantly exposed to P. falciparum cross-recognized the rPvs48/45 protein. This, together with the functional activity of IgG, warrants further studies for the potential development of a P. vivax and P. falciparum cross-protective TB vaccine.
Authors
- Myriam Arévalo‐Herrera (ORCID: https://orcid.org/0000-0002-3434-9425)
- Sonia M. Herrera
- Carole A. Long (ORCID: https://orcid.org/0000-0002-3835-5443)
- Saidou Balam (ORCID: https://orcid.org/0000-0002-7178-7758)
- Sope Olugbile
- Issa Nébié (ORCID: https://orcid.org/0000-0003-3051-3600)
- Andrey V. Kajava (ORCID: https://orcid.org/0000-0002-2342-6886)
- Nathan C. Incandela
- Valentina Agnolon (ORCID: https://orcid.org/0000-0002-4950-239X)
- Drissa Konaté (ORCID: https://orcid.org/0000-0002-4177-9642)
- Imen Ayadi (ORCID: https://orcid.org/0000-0003-4325-4900)
- Seidina A. S. Diakité (ORCID: https://orcid.org/0000-0003-1193-6501)
- Kazutoyo Miura (ORCID: https://orcid.org/0000-0003-4455-2432)
- Mahamadou Diakité (ORCID: https://orcid.org/0000-0002-4268-8857)
- Giampietro Corradin
- Merepen A. Guindo
- Sócrates Herrera
Institutions
- National Institutes of Health (US)
- Université de Montpellier (FR)
- Centre Hospitalier Universitaire Vaudois (CH)
- Université des Sciences, des Techniques et des Technologies de Bamako (ML)
- Caucaseco Scientific Research Center (CO)
- National Institute of Allergy and Infectious Diseases (US)
- Groupe de Recherche et d’Action sur le Foncier (BF)
- University of Lausanne (CH)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1371/journal.pone.0302605
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases