Characterization of a multidrug-resistant hypovirulent ST1859-KL35 klebsiella quasipneumoniae subsp. similipneumoniae strain co-harboring tmexCD2-toprJ2 and bla
KP24 represents a hypovirulent yet multidrug-resistant strain of K. quasipneumoniae subsp. similipneumoniae, with a concerning combination of virulence and resistance determinants. The co-location of tmexCD2-toprJ2 and bla<sub>KPC-2</sub> on a transferable plasmid highlights the potential for horizontal gene transfer of critical resistance mechanisms.
Authors
- Jenghwa Chang (ORCID: https://orcid.org/0000-0002-9632-6317)
- Zhekai Hu (ORCID: https://orcid.org/0000-0001-5865-8225)
- Lei Feng (ORCID: https://orcid.org/0000-0003-2377-0190)
- Mingjie Zhang (ORCID: https://orcid.org/0000-0001-9404-0190)
- Jiawei Ding
- Pei He
- Jia Wang (ORCID: https://orcid.org/0000-0002-2330-8505)
Institutions
- Kunming Medical University (CN)
- Yan'an Hospital Affiliated To Kunming Medical University (CN)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1016/j.jgar.2025.03.009
- Citations
- 3
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 5.15