Mathematical and Numerical Modeling of the Pluripotency Gene Network Dynamics
We consider nonlinear dynamical systems as models of interaction of components of a gene network which regulates early stages of an embryonic stem cells state. A parametric analysis of these dynamical systems is performed in order to describe the (non)uniqueness and stability of their equilibriums. We have obtained a criterion of existence of periodic trajectories near these points and localized such oscillations on the phase portraits of dynamical systems which describe these processes. A special software for cloud numerical experiments with such systems has been elaborated.
Authors
- V. P. Golubyatnikov (ORCID: https://orcid.org/0000-0002-9758-3833)
- E. A. Tatarinova
Institutions
- Novosibirsk State University (RU)
Publication Details
- Journal
- Numerical Analysis and Applications
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1134/s1995423925010033
- Primary Topic
- Gene Regulatory Network Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00