Pre-eclampsia Complicated by HELLP Syndrome in a Primigravida: A Case Report
Pre-eclampsia is a hypertensive disorder of pregnancy that can rapidly progress to HELLP syndrome, increasing maternal and fetal risks. We report a case of a 33-year-old primigravida at 28+1 weeks gestation who presented with severe hypertension, proteinuria, and reduced fetal movements. Despite initial management, she developed progressive thrombocytopenia, worsening liver function, and oligohydramnios, necessitating close monitoring. Biochemical markers indicated worsening disease, prompting an emergency cesarean section at 28+6 weeks, delivering a growth-restricted neonate. Postoperatively, the patient showed gradual improvement, and histopathology confirmed placental malperfusion. This case underscores the importance of early recognition, biochemical monitoring, and timely delivery in managing severe pre-eclampsia and preventing life-threatening complications.
Authors
- Mohamed A. Ismail (ORCID: https://orcid.org/0000-0001-5059-4220)
- Eman Abdel-Salam Ibrahim (ORCID: https://orcid.org/0000-0002-1916-3681)
- Nabeelah Ismail
Institutions
- Thumbay Group (United Arab Emirates) (AE)
Publication Details
- Journal
- Cureus
- Published
- 2025-03-18
- DOI
- https://doi.org/10.7759/cureus.80770
- Citations
- 1
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 2.06