Pre-eclampsia Complicated by HELLP Syndrome in a Primigravida: A Case Report

Pre-eclampsia is a hypertensive disorder of pregnancy that can rapidly progress to HELLP syndrome, increasing maternal and fetal risks. We report a case of a 33-year-old primigravida at 28+1 weeks gestation who presented with severe hypertension, proteinuria, and reduced fetal movements. Despite initial management, she developed progressive thrombocytopenia, worsening liver function, and oligohydramnios, necessitating close monitoring. Biochemical markers indicated worsening disease, prompting an emergency cesarean section at 28+6 weeks, delivering a growth-restricted neonate. Postoperatively, the patient showed gradual improvement, and histopathology confirmed placental malperfusion. This case underscores the importance of early recognition, biochemical monitoring, and timely delivery in managing severe pre-eclampsia and preventing life-threatening complications.

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Publication Details

Journal
Cureus
Published
2025-03-18
DOI
https://doi.org/10.7759/cureus.80770
Citations
1
Primary Topic
Pregnancy and preeclampsia studies
Type
article
Field-Weighted Citation Impact
2.06
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article

Pre-eclampsia Complicated by HELLP Syndrome in a Primigravida: A Case Report

Mohamed A. Ismail, Eman Abdel-Salam Ibrahim, Nabeelah Ismail
1 citations
Cureus
Pregnancy and preeclampsia studies
2.06
article

Pre-eclampsia Complicated by HELLP Syndrome in a Primigravida: A Case Report

Mohamed A. Ismail, Eman Abdel-Salam Ibrahim, Nabeelah Ismail
article en
1 citations

Abstract

Pre-eclampsia is a hypertensive disorder of pregnancy that can rapidly progress to HELLP syndrome, increasing maternal and fetal risks. We report a case of a 33-year-old primigravida at 28+1 weeks gestation who presented with severe hypertension, proteinuria, and reduced fetal movements. Despite initial management, she developed progressive thrombocytopenia, worsening liver function, and oligohydramnios, necessitating close monitoring. Biochemical markers indicated worsening disease, prompting an emergency cesarean section at 28+6 weeks, delivering a growth-restricted neonate. Postoperatively, the patient showed gradual improvement, and histopathology confirmed placental malperfusion. This case underscores the importance of early recognition, biochemical monitoring, and timely delivery in managing severe pre-eclampsia and preventing life-threatening complications.

CureusVol. 17(3)
Thumbay Group (United Arab Emirates) (AE)
Gender equality
Openalex Percentile: Top 17%
Pregnancy and preeclampsia studies
2.06
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