Laparoscopic lavage in a purulent peritonitis model: impact on inflammatory proteins
Our animal model is reproducible, and mimics perforated diverticulitis with purulent peritonitis with increased levels of inflammatory proteins in abdominal fluid and serum. The levels of several inflammatory proteins were lower following laparoscopic lavage treatment perhaps indicating the physiological effect of laparoscopic lavage. This model can be used to further explore the mechanisms involved in peritonitis and laparoscopic lavage treatment.
Authors
- Maria K. Magnusson (ORCID: https://orcid.org/0000-0002-8888-4968)
- Lena Öhman (ORCID: https://orcid.org/0000-0001-8142-2106)
- Eva Angenete (ORCID: https://orcid.org/0000-0001-9966-4904)
- Mattias Prytz (ORCID: https://orcid.org/0000-0002-3939-927X)
- Viktor Tasselius
- Erik Sinclair
- Eva Haglind
Institutions
- Sahlgrenska University Hospital (SE)
- Region Västra Götaland (SE)
- NU Hospital Group (SE)
- University of Gothenburg (SE)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1186/s40001-025-02445-2
- Primary Topic
- Diverticular Disease and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Göteborgs Universitet