Analysis of risk factors for recurrence after laparoscopic myomectomy: A retrospective study

At present, there is unclear on the risk factors of recurrence after myomectomy. In this study, we hope to provide reference for the choice of treatment for patients with uterine fibroids and provide basis for the subsequent prediction of recurrence. From October 2020 to October 2022, we enrolled 240 patients with uterine fibroids in Hubei Maternal and Child Health Hospital. According to the inclusion criteria, the collected clinical data of these patients were analyzed and divided into 2 groups according to whether there was recurrence 6 months after surgery(a recurrence group [52 cases] and a non-recurrence group [78 cases]). We compared and analyzed the relevant factors. Univariate analysis showed that there was no significant relationship between fibroid diameter, postoperative pregnancy, contraceptive method, hyperlipidemia, diabetes, endometriosis and postoperative recurrence (P > .05). While, age, number of pregnancies, number of fibroids, type of fibroids, body mass index, endometrial hyperplasia or endometrial polyp were significantly correlated with postoperative recurrence (P < .05). Multivariate Logistic regression analysis demonstrated that body mass index > 24, number of pregnancies > 2, multiple myoma, intermyoma and endometrial hyperplasia were independent risk factors for postoperative myoma recurrence (P < .05). Body mass index > 24, number of pregnancies > 2, multiple fibroids, intermyowall fibroids, and endometrial hyperplasia are all independent risk factors for recurrence after laparoscopic myomectomy in patients with uterine fibroids. Patients with these independent risk factors should be closely reviewed. If they have multiple independent risk factors and have no fertility requirements are present, hysterectomy may be recommended.