Impact of basal infusion on postoperative nausea and vomiting in fentanyl-based intravenous patient-controlled analgesia: A randomized controlled trial

Fentanyl-based IV PCA without basal infusion resulted in less postoperative nausea and vomiting than IV PCA with basal infusion and maintained adequate analgesia. Basal infusion can be omitted to reduce postoperative nausea using IV PCA by applying an appropriate lock-out interval. Further research comparing variable PCA settings is warranted.

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Publication Details

Journal
Medicine
Published
2025-03-14
DOI
https://doi.org/10.1097/md.0000000000041813
Primary Topic
Nausea and vomiting management
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of basal infusion on postoperative nausea and vomiting in fentanyl-based intravenous patient-controlled analgesia: A randomized controlled trial

Seung Woo Song, Sujin Kim, Yun Hyung Cho, Yeong-Gwan Jeon et al.
Medicine
Nausea and vomiting management
article

Impact of basal infusion on postoperative nausea and vomiting in fentanyl-based intravenous patient-controlled analgesia: A randomized controlled trial

Seung Woo Song, Sujin Kim, Yun Hyung Cho, Yeong-Gwan Jeon, Ji-Hyoung Park, Jimmy Bok Yan So
article en

Abstract

Fentanyl-based IV PCA without basal infusion resulted in less postoperative nausea and vomiting than IV PCA with basal infusion and maintained adequate analgesia. Basal infusion can be omitted to reduce postoperative nausea using IV PCA by applying an appropriate lock-out interval. Further research comparing variable PCA settings is warranted.

MedicineVol. 104(11)
Yonsei University (KR), Wonju Severance Christian Hospital (KR)
Good health and well-being
Openalex Percentile: Top 91%
Nausea and vomiting management
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Impact of basal infusion on postoperative nausea and vomiting in fentanyl-based intravenous patient-controlled analgesia: A randomized controlled trial — Seung Woo Song, Sujin Kim, et al. · Medicine (2025) | TGRS Research Map | TGRS