Clinical characteristics and impact of exchange transfusion in infant pertussis with extreme leukocytosis

Extreme hyperleukocytosis is more commonly observed in young female children with pertussis. Younger age, unvaccinated status, and the presence of concurrent heart failure and PH may be associated with a poor prognosis. ET can effectively reduce peripheral blood leukocytes, but a rapid leukocyte rebound post-ET may be indicative of impending death.

Authors

Institutions

Publication Details

Journal
˜The œItalian Journal of Pediatrics/Italian journal of pediatrics
Published
2025-03-18
DOI
https://doi.org/10.1186/s13052-025-01933-9
Citations
7
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
9.48

Funders

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article

Clinical characteristics and impact of exchange transfusion in infant pertussis with extreme leukocytosis

Chuan Gan, Yuanyuan Wu
7 citations
˜The œItalian Journal of Pediatrics/Italian journal of pediatrics
Pneumonia and Respiratory Infections
9.48
article

Clinical characteristics and impact of exchange transfusion in infant pertussis with extreme leukocytosis

Chuan Gan, Yuanyuan Wu
article en
7 citations

Abstract

Extreme hyperleukocytosis is more commonly observed in young female children with pertussis. Younger age, unvaccinated status, and the presence of concurrent heart failure and PH may be associated with a poor prognosis. ET can effectively reduce peripheral blood leukocytes, but a rapid leukocyte rebound post-ET may be indicative of impending death.

˜The œItalian Journal of Pediatrics/Italian journal of pediatricsVol. 51(1)
Dalian Medical University (CN), Second Affiliated Hospital of Chongqing Medical University (CN), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Chongqing
Good health and well-being
Openalex Percentile: Top 2%
Pneumonia and Respiratory Infections
9.48
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