Therapeutic Targets for Gastric Cancer: Mendelian Randomization and Colocalization Analysis
Our research examined the causal relationship between plasma proteins and gastric cancer, shedding light on potential therapeutic targets. These findings have significant implications for the development of early diagnostic markers and targeted therapies for GC, potentially improving patient outcomes and survival rates. Future studies should validate these findings in diverse populations and explore the clinical applications of these targets.
Authors
- Liu Zd (ORCID: https://orcid.org/0000-0003-0811-3571)
- Yong Wang (ORCID: https://orcid.org/0000-0003-4061-7956)
- Ying Sun (ORCID: https://orcid.org/0000-0002-3104-4394)
- Wenjia Liu (ORCID: https://orcid.org/0000-0001-8034-4425)
- Zongkai Liu (ORCID: https://orcid.org/0000-0002-8862-9537)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Biological Procedures Online
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1186/s12575-025-00273-6
- Citations
- 2
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Key Technology Research and Development Program of Shandong