Blaschko-Linear Dermatoses: Lichen Striatus with Blaschkitis

Lichen striatus is a rare dermatological condition predominantly affecting pediatric populations, characterized by an erythematous rash of elevated papules forming linear bands along Blaschko's lines. Its etiology remains unclear, though links to environmental factors and atopy are suggested. Blaschkitis, another uncommon inflammatory condition, presents with pruritic papules and vesicular eruptions along the same lines, thought to result from genetically abnormal keratinocytes triggering a T-cell mediated response. This report details a case of a 13-year-old female presenting with hyperpigmented lesions in the axilla, leading to a differential diagnosis of lichen striatus, blaschkitis, and melanocytic nevi. Histopathological analysis confirmed findings consistent with lichen striatus and features of blaschkitis. While the occurrence of these conditions together is rare, their potential interplay warrants further investigation to enhance understanding of their pathophysiology and inform therapeutic approaches. This case highlights the need for continued research into these enigmatic dermatological disorders, particularly within pediatric populations.

Authors

Publication Details

Journal
South Eastern European Journal of Public Health
Published
2025-02-19
DOI
https://doi.org/10.70135/seejph.vi.4771
Primary Topic
Genetic and rare skin diseases.
Type
article
Field-Weighted Citation Impact
0.00
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article

Blaschko-Linear Dermatoses: Lichen Striatus with Blaschkitis

Kalyan Dalave, Aditi Gupta, Priyanka Kumari, Aravind Reddy
South Eastern European Journal of Public Health
Genetic and rare skin diseases.
article

Blaschko-Linear Dermatoses: Lichen Striatus with Blaschkitis

Kalyan Dalave, Aditi Gupta, Priyanka Kumari, Aravind Reddy
article en

Abstract

Lichen striatus is a rare dermatological condition predominantly affecting pediatric populations, characterized by an erythematous rash of elevated papules forming linear bands along Blaschko's lines. Its etiology remains unclear, though links to environmental factors and atopy are suggested. Blaschkitis, another uncommon inflammatory condition, presents with pruritic papules and vesicular eruptions along the same lines, thought to result from genetically abnormal keratinocytes triggering a T-cell mediated response. This report details a case of a 13-year-old female presenting with hyperpigmented lesions in the axilla, leading to a differential diagnosis of lichen striatus, blaschkitis, and melanocytic nevi. Histopathological analysis confirmed findings consistent with lichen striatus and features of blaschkitis. While the occurrence of these conditions together is rare, their potential interplay warrants further investigation to enhance understanding of their pathophysiology and inform therapeutic approaches. This case highlights the need for continued research into these enigmatic dermatological disorders, particularly within pediatric populations.

South Eastern European Journal of Public Health
Openalex Percentile: Top 94%
Genetic and rare skin diseases.
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Blaschko-Linear Dermatoses: Lichen Striatus with Blaschkitis — Kalyan Dalave, Aditi Gupta, et al. · South Eastern European Journal of Public Health (2025) | TGRS Research Map | TGRS