Comprehensive immunophenotyping of gastric adenocarcinoma identifies an inflamed class of tumors amenable to immunotherapies
Comprehensive immunophenotyping of GAC identifies an inflamed class of tumors that complements previously proposed tumor-based molecular clusters. Such findings may provide the rationale for exploring novel immunotherapeutic approaches for biomarker-enriched populations in order to improve GAC patient's survival.
Authors
- Eva Parisi (ORCID: https://orcid.org/0000-0001-5891-7530)
- F Vilardell (ORCID: https://orcid.org/0000-0002-0876-5425)
- Robert Montal (ORCID: https://orcid.org/0000-0002-8455-4232)
- Maria Alba Sorolla (ORCID: https://orcid.org/0000-0002-2180-0408)
- Maria Ruiz (ORCID: https://orcid.org/0000-0001-6900-4382)
- Alfredo Escartín (ORCID: https://orcid.org/0000-0002-5234-2366)
- Carles Aracil (ORCID: https://orcid.org/0000-0002-8228-9041)
- Anabel Sorolla (ORCID: https://orcid.org/0000-0001-8238-8763)
- Xavier Matías‐Guiu (ORCID: https://orcid.org/0000-0002-7201-6605)
- M Piñol (ORCID: https://orcid.org/0000-0002-2073-0241)
- Antonieta Salud (ORCID: https://orcid.org/0000-0002-7399-7484)
- Marı́a Santacana (ORCID: https://orcid.org/0000-0003-1975-2598)
- Genı́s Parra (ORCID: https://orcid.org/0000-0002-0575-2936)
- Joel Veas Rodríguez (ORCID: https://orcid.org/0000-0002-8786-1406)
- Mar Iglesias (ORCID: https://orcid.org/0000-0002-2274-4671)
- Mario Bernabeu
Institutions
- Universitat Pompeu Fabra (ES)
- Hospital Universitari Arnau de Vilanova (ES)
- Hospital Del Mar (ES)
- Centre for Genomic Regulation (ES)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1136/jitc-2024-010024
- Citations
- 5
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 5.23
Funders
- European Commission
- Sociedad Española de Oncología Médica
- Xarxa de Bancs de Tumors de Catalunya
- Agència de Gestió d'Ajuts Universitaris i de Recerca
- Instituto de Salud Carlos III