Insights into the DNA damage response and tumor drug resistance
DDR is a highly coordinated signaling network that repairs DNA damage caused by intrinsic cellular processes and extrinsic insults, thereby preventing genome instability. Depending on the type of damage, distinct DNA damage repair and DNA damage tolerance (DDT) pathways are involved and coordinately
Authors
- Xiaolu Ma (ORCID: https://orcid.org/0000-0003-3960-5720)
- Caixia Guo (ORCID: https://orcid.org/0000-0002-2820-705X)
- Zina Cheng
Institutions
- Chinese Academy of Sciences (CN)
- Beijing Institute of Genomics (CN)
- Shanghai Center For Bioinformation Technology (CN)
- University of Chinese Academy of Sciences (CN)
- Taiyuan University of Technology (CN)
Publication Details
- Journal
- Cancer Biology and Medicine
- Published
- 2025-03-18
- DOI
- https://doi.org/10.20892/j.issn.2095-3941.2025.0020
- Citations
- 3
- Primary Topic
- Cancer therapeutics and mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.42