Jaboticaba's hidden power: unveiling the hepatoprotective effects of phenolic extracts

Abstract This commentary discusses the significant findings of a study on Jaboticaba peel phenolic extract (JPPE) and its protective effects against oxidative stress and liver fat accumulation in rabbits fed a high cholesterol diet. The research highlights JPPE's ability to reduce serum biomarkers associated with hepatic damages, prevent lipid peroxidation, and restore antioxidant enzyme activities in those animals. By emphasizing the underutilized potential of Jaboticaba peels, this commentary advocates for further exploration of phenolic compounds as natural therapeutic agents in the prevention and management of hepatic diseases induced by high cholesterol diet. Ultimately, it underscores the importance of integrating such functional foods into dietary practices for enhancing liver health. These findings suggest that supplementation of JPPE into human diets could offer a promising natural strategy for reducing the risk of metabolic dysfunction-associated steatotic liver disease and improving the overall liver health, particularly in populations at risk due to poor dietary habits. Graphical Abstract