Exploring the origins of frequent tau-PET signal in vermal and adjacent regions
Leptomeningeal melanocytes are the primary target structure for [<sup>18</sup>F]PI-2620 PET binding in anterior vermis, whereas iron and tau deposits do not contribute significantly.
Authors
- Alexander Jäck (ORCID: https://orcid.org/0000-0003-0183-4392)
- Lars Paeger (ORCID: https://orcid.org/0000-0001-8716-3483)
- Gérard N. Bischof (ORCID: https://orcid.org/0000-0002-4366-5171)
- Osama Sabri (ORCID: https://orcid.org/0000-0002-6425-3504)
- Luna Slemann
- Michael Rullmann (ORCID: https://orcid.org/0000-0002-2683-9432)
- Maximilian Scheifele
- A. Bernhardt (ORCID: https://orcid.org/0000-0001-9974-8091)
- Henryk Barthel (ORCID: https://orcid.org/0000-0002-9322-9167)
- Johannes Levin (ORCID: https://orcid.org/0000-0001-5092-4306)
- Carla Palleis (ORCID: https://orcid.org/0000-0002-4331-8145)
- Johannes Gnörich (ORCID: https://orcid.org/0000-0003-1554-7765)
- Sebastian Niclas Roemer (ORCID: https://orcid.org/0000-0003-3423-457X)
- Sigrun Roeber
- Günter U. Höglinger (ORCID: https://orcid.org/0000-0001-7587-6187)
- Jochen Herms (ORCID: https://orcid.org/0000-0002-6201-1042)
- Mirlind Zaganjori (ORCID: https://orcid.org/0009-0000-5740-4549)
- Thilo van Eimeren (ORCID: https://orcid.org/0000-0002-6951-2325)
- Lukas Frontzkowski (ORCID: https://orcid.org/0000-0001-9321-956X)
- Alexander Drzezga (ORCID: https://orcid.org/0000-0001-6018-716X)
- Nicolai Franzmeier (ORCID: https://orcid.org/0000-0001-9736-2283)
- Julia Kusche‐Palenga
- A. Kling
- Matthias Brendel
Institutions
- Forschungszentrum Jülich (DE)
- German Center for Neurodegenerative Diseases (DE)
- LMU Klinikum (DE)
- Munich Cluster for Systems Neurology (DE)
- University Hospital Leipzig (DE)
- University Hospital Cologne (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Gothenburg (SE)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1007/s00259-025-07199-x
- Citations
- 4
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 3.64