Paraneoplastic Leucine Zipper 4 <scp>IgG</scp> Associated Motor‐Predominant Polyradiculoneuropathy
LUZP4-IgG seropositivity and identification of retroperitoneal seminoma confirmed a paraneoplastic neurologic syndrome, which is a CD8+ T-cell-mediated disorder. Aggressive immunotherapy was initiated, resulting in clinical improvement. This case underscores the importance of identifying specific serologic biomarkers that can inform therapeutic decisions and improve outcomes.
Authors
- Brendan Putko (ORCID: https://orcid.org/0000-0001-8500-2360)
- Richard A. Lewis (ORCID: https://orcid.org/0000-0001-5475-3890)
- Marcus Vinícius Pinto (ORCID: https://orcid.org/0000-0002-9890-6657)
- Duaa Jabari
- Divyanshu Dubey (ORCID: https://orcid.org/0000-0001-6865-9045)
- Catherine Daley
- Alex Panrudkevich
Institutions
- Cedars-Sinai Medical Center (US)
- Mayo Clinic (US)
- WinnMed (US)
Publication Details
- Journal
- Journal of the Peripheral Nervous System
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/jns.70013
- Citations
- 1
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.77