Hydroxycotinine exhibits a stronger association with chronic kidney disease in smokers when compared to cotinine: Evidence from NHANES 2013–2018
Elevated serum concentrations of cotinine and hydroxycotinine are positively associated with low glomerular filtration rate, albuminuria, and CKD in smokers, with hydroxycotinine demonstrating a stronger correlation. Smoking is established as a heightened risk factor for CKD, thus avoidance or reduction of smoking is strongly recommended.
Authors
- Yaning Wang
- Cihang Lu (ORCID: https://orcid.org/0000-0003-1415-4927)
- Ning Jia (ORCID: https://orcid.org/0000-0001-6434-170X)
- Zhiqiang Liu (ORCID: https://orcid.org/0000-0003-2951-6150)
- Yue Xu
- Shan Zheng (ORCID: https://orcid.org/0000-0002-3708-9219)
- S Zhao (ORCID: https://orcid.org/0009-0002-3419-1231)
Institutions
- Shandong University of Aeronautics (CN)
- Capital Medical University (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
- China Medical University (CN)
Publication Details
- Journal
- Tobacco Induced Diseases
- Published
- 2025-03-18
- DOI
- https://doi.org/10.18332/tid/201969
- Citations
- 2
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.78