Prevalence of autoimmune diabetes among Aboriginal Australians: the Fremantle Diabetes Study Phase <scp>II</scp>

The prevalence of autoimmune diabetes was assessed in 113 indigenous and 1555 non-indigenous participants in the Fremantle Diabetes Study Phase II. Both type 1 diabetes (3.5% vs. 8.2%) and latent autoimmune diabetes of adults diagnosed based on glutamic acid decarboxylase antibody (GADA) positivity (1.0% vs. 5.7%) were lower in Aboriginal participants (P = 0.101 and 0.039 respectively). Six Aboriginals with GADA-negative type 2 diabetes were positive for tyrosine phosphatase-related islet antigen 2 antibodies but did not exhibit relative insulin deficiency.

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Publication Details

Journal
Internal Medicine Journal
Published
2025-03-18
DOI
https://doi.org/10.1111/imj.70029
Citations
1
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
1.82

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article

Prevalence of autoimmune diabetes among Aboriginal Australians: the Fremantle Diabetes Study Phase II

S. A. Paul Chubb, Wendy A. Davis, Timothy M. E. Davis, Christine Bundell et al.
1 citations
Internal Medicine Journal
Diabetes and associated disorders
1.82
article

Prevalence of autoimmune diabetes among Aboriginal Australians: the Fremantle Diabetes Study Phase II

S. A. Paul Chubb, Wendy A. Davis, Timothy M. E. Davis, Christine Bundell, Daniel R. McAullay
article en
1 citations

Abstract

The prevalence of autoimmune diabetes was assessed in 113 indigenous and 1555 non-indigenous participants in the Fremantle Diabetes Study Phase II. Both type 1 diabetes (3.5% vs. 8.2%) and latent autoimmune diabetes of adults diagnosed based on glutamic acid decarboxylase antibody (GADA) positivity (1.0% vs. 5.7%) were lower in Aboriginal participants (P = 0.101 and 0.039 respectively). Six Aboriginals with GADA-negative type 2 diabetes were positive for tyrosine phosphatase-related islet antigen 2 antibodies but did not exhibit relative insulin deficiency.

Internal Medicine JournalVol. 55(4)
Edith Cowan University (AU), The University of Western Australia (AU), Fiona Stanley Hospital (AU), Fremantle Hospital (AU), Queen Elizabeth II Medical Centre (AU), Pathwest Laboratory Medicine (AU)
Medical Research Council, National Health and Medical Research Council
Good health and well-being
Openalex Percentile: Top 18%
Diabetes and associated disorders
1.82
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