Efficacy and safety of pulsatile GnRH pump therapy in male infants with congenital hypogonadotropic hypogonadism

Pulsatile gonadotropin-releasing hormone pump therapy can increase penile length, testicular volume, anti-Müllerian hormone levels and serum inhibin B levels in infants with congenital hypogonadotropic hypogonadism without adverse effects. However, its long-term efficacy and safety require further follow-up.

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Publication Details

Journal
Endocrine Connections
Published
2025-03-18
DOI
https://doi.org/10.1530/ec-24-0655
Primary Topic
Sexual Differentiation and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of pulsatile GnRH pump therapy in male infants with congenital hypogonadotropic hypogonadism

Dongxia Fu, Mengmeng Du, Zixia Zhang, Jiajia Chen et al.
Endocrine Connections
Sexual Differentiation and Disorders
article

Efficacy and safety of pulsatile GnRH pump therapy in male infants with congenital hypogonadotropic hypogonadism

Dongxia Fu, Mengmeng Du, Zixia Zhang, Jiajia Chen, Xi Wang, Haiyan Wei, Yongxing Chen
article en

Abstract

Pulsatile gonadotropin-releasing hormone pump therapy can increase penile length, testicular volume, anti-Müllerian hormone levels and serum inhibin B levels in infants with congenital hypogonadotropic hypogonadism without adverse effects. However, its long-term efficacy and safety require further follow-up.

Endocrine ConnectionsVol. 14(5)
Capital Medical University (CN), Zhengzhou Children's Hospital (CN), Beijing Children’s Hospital (CN)
Good health and well-being
Openalex Percentile: Top 95%
Sexual Differentiation and Disorders
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Efficacy and safety of pulsatile GnRH pump therapy in male infants with congenital hypogonadotropic hypogonadism — Dongxia Fu, Mengmeng Du, et al. · Endocrine Connections (2025) | TGRS Research Map | TGRS