Prevalence of Aspirin or Clopidogrel Pharmacological Resistance in Ischemic Stroke: A Step Toward Precision Medicine

The present result demonstrated that a sizeable portion of the population has inefficacious activity in the setting of specific antiplatelet agents. Additionally, sex and ethnicity differences in responsiveness to aspirin or clopidogrel have been noted. Determining a patient's response to medications could provide opportunities to individualize treatment and better prevent future strokes. Further studies of a larger scale are indeed needed to apply this information to pursue individualized treatment.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2025-03-01
DOI
https://doi.org/10.1111/cns.70343
Citations
5
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
6.94
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article

Prevalence of Aspirin or Clopidogrel Pharmacological Resistance in Ischemic Stroke: A Step Toward Precision Medicine

Laurel Packard, Małgorzata Miller, Asad Ahrar, Jiangyong Min et al.
5 citations
CNS Neuroscience & Therapeutics
Antiplatelet Therapy and Cardiovascular Diseases
6.94
article

Prevalence of Aspirin or Clopidogrel Pharmacological Resistance in Ischemic Stroke: A Step Toward Precision Medicine

Laurel Packard, Małgorzata Miller, Asad Ahrar, Jiangyong Min, Nabil Wees, Nadeem Khan, Samantha Cencer, Alan T. Davis
article en
5 citations

Abstract

The present result demonstrated that a sizeable portion of the population has inefficacious activity in the setting of specific antiplatelet agents. Additionally, sex and ethnicity differences in responsiveness to aspirin or clopidogrel have been noted. Determining a patient's response to medications could provide opportunities to individualize treatment and better prevent future strokes. Further studies of a larger scale are indeed needed to apply this information to pursue individualized treatment.

CNS Neuroscience & TherapeuticsVol. 31(3)
Grand Rapids Community College (US), Michigan State University (US)
Good health and well-being
Openalex Percentile: Top 3%
Antiplatelet Therapy and Cardiovascular Diseases
6.94
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