Prevalence of Aspirin or Clopidogrel Pharmacological Resistance in Ischemic Stroke: A Step Toward Precision Medicine
The present result demonstrated that a sizeable portion of the population has inefficacious activity in the setting of specific antiplatelet agents. Additionally, sex and ethnicity differences in responsiveness to aspirin or clopidogrel have been noted. Determining a patient's response to medications could provide opportunities to individualize treatment and better prevent future strokes. Further studies of a larger scale are indeed needed to apply this information to pursue individualized treatment.
Authors
- Laurel Packard
- Małgorzata Miller (ORCID: https://orcid.org/0000-0002-7445-6217)
- Asad Ahrar
- Jiangyong Min (ORCID: https://orcid.org/0000-0001-7730-3139)
- Nabil Wees
- Nadeem Khan (ORCID: https://orcid.org/0000-0001-7221-6597)
- Samantha Cencer (ORCID: https://orcid.org/0000-0001-5255-971X)
- Alan T. Davis
Institutions
- Grand Rapids Community College (US)
- Michigan State University (US)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/cns.70343
- Citations
- 5
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 6.94