IGV-001 cellular immunotherapy for newly diagnosed glioblastoma: overcoming the logistic challenge
We have learned a great deal in the process of developing and executing our internal procedures for this clinical trial. Our description of the IGV-001 protocol workflow may serve as a "blueprint" for future implementation of this type of cellular immunotherapy at other centers. We further discuss some of the lessons we have learned during the trial.
Authors
- Athar N. Malik (ORCID: https://orcid.org/0000-0002-1545-4107)
- Curt Doberstein
- John E. Donahue (ORCID: https://orcid.org/0000-0001-7186-2562)
- Jennifer Dailey
- Attila A. Seyhan (ORCID: https://orcid.org/0000-0003-1276-8466)
- Sasmit Sarangi (ORCID: https://orcid.org/0000-0002-9002-3139)
- Konstantina A. Svokos (ORCID: https://orcid.org/0000-0002-2279-9453)
- Hael Abdulrazeq
- Neil P. Rodrigues (ORCID: https://orcid.org/0000-0002-1925-7733)
- Heinrich Elinzano
- Rahul A. Sastry (ORCID: https://orcid.org/0000-0001-5129-2179)
- Esther Yee Tak Yu (ORCID: https://orcid.org/0000-0001-7472-7083)
- Belinda Shao (ORCID: https://orcid.org/0000-0002-6392-0643)
- Joshua Feler (ORCID: https://orcid.org/0000-0002-9206-6394)
- Tori Riccelli (ORCID: https://orcid.org/0000-0001-8397-3948)
- Ziya L. Gokaslan (ORCID: https://orcid.org/0009-0003-9962-6141)
- Elaina Wang (ORCID: https://orcid.org/0009-0005-5321-0313)
- Carlin Chuck (ORCID: https://orcid.org/0000-0001-5735-2654)
- Elias Shaaya (ORCID: https://orcid.org/0000-0002-2243-7954)
- Deus Cielo
- Sharonda E. Keith (ORCID: https://orcid.org/0000-0002-2510-0572)
- Howard Safran
- Michael Punsoni
- Wafik S. El‐Deiry (ORCID: https://orcid.org/0000-0002-9577-8266)
- Rohaid Ali (ORCID: https://orcid.org/0000-0002-6509-0129)
- Fei Sun (ORCID: https://orcid.org/0000-0002-0870-8375)
- Christine Yu (ORCID: https://orcid.org/0000-0002-1317-5825)
- Prakash Sampath (ORCID: https://orcid.org/0000-0001-5994-6819)
- Clark C. Chen (ORCID: https://orcid.org/0000-0001-6258-9277)
- Jerrold L. Boxerman (ORCID: https://orcid.org/0000-0001-5972-4597)
- Eric T. Wong
- Robert P. Edwards
- Santos E. Santos Fontánez
- Natalie Amaral Nieves
- Cody Dobertsein
- Francesca Rothell
Institutions
- Brown University (US)
- Rhode Island Hospital (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-03-18
- DOI
- https://doi.org/10.3389/fonc.2025.1556450
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00