Modern respiratory epithelium protection mechanisms

N-acetylcysteine (Fluimucil) is characterized by high antioxidant potential due to direct effect on both free radicals through inhibition of free radical reactions, including those related to the mechanisms underlying the iron-dependent cell death (ferroptosis), and the synthesis of the antioxidant molecules constituting the antioxidant protection system. The review is focused on the N-acetylcysteine involvement in the development of antioxidant protection and on the use of high doses of N-acetylcysteine in combination with thiamphenicol for treatment of bacterial infections.