Artichoke water extract protects against Lead-induced hepatotoxicity by activating Nrf2 signaling and inhibiting NLRP3/caspase-1/GSDMD-mediated pyroptosis
These findings indicate that AWE protects against Pb-induced liver toxicity potentially through its chelating, antioxidant, and anti-inflammatory properties.
Authors
- Meng Xue
- Mengyuan Yi
- Xiaowei Ding
- Ping Mo (ORCID: https://orcid.org/0000-0001-7102-5772)
- Shaogang Fan (ORCID: https://orcid.org/0009-0009-3345-7780)
- Kerui Huang (ORCID: https://orcid.org/0000-0003-1866-8407)
- Peng Xie (ORCID: https://orcid.org/0000-0002-9138-9749)
- Aihua Deng (ORCID: https://orcid.org/0000-0003-3482-0827)
- Yun Wang (ORCID: https://orcid.org/0000-0003-3661-9959)
- Bing Xiao (ORCID: https://orcid.org/0000-0002-3736-6714)
Institutions
- Hunan University of Arts and Science (CN)
- XinHua Hospital (CN)
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2025-03-18
- DOI
- https://doi.org/10.1016/j.jep.2025.119654
- Citations
- 4
- Primary Topic
- Cynara cardunculus studies
- Type
- article
- Field-Weighted Citation Impact
- 7.00