Systolic Ejection Murmur in a Case of Patent Ductus Arteriosus and Pulmonary Hypertension With Liver Cirrhosis

Patent ductus arteriosus (PDA) is a congenital anomaly characterized by a persistent connection between the descending aorta and the pulmonary artery. While patients with PDA typically present with a continuous murmur, atypical cases, such as those with systolic murmurs or no murmurs (although the exact mechanism remains unclear), pose diagnostic challenges. We report a case of a 38-year-old woman with alcoholic liver cirrhosis, referred for liver transplantation, in whom a systolic ejection murmur prompted further evaluation. Diagnostic imaging and right heart catheterization confirmed PDA with mild pulmonary hypertension, without evidence of Eisenmenger physiology. This case underscores the importance of recognizing atypical murmur patterns in the diagnosis of PDA to avoid misdiagnosis or delayed diagnosis.

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Publication Details

Journal
Cureus
Published
2025-03-16
DOI
https://doi.org/10.7759/cureus.80691
Primary Topic
Cardiovascular Conditions and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Systolic Ejection Murmur in a Case of Patent Ductus Arteriosus and Pulmonary Hypertension With Liver Cirrhosis

Michiyo Yamano, Tatsuya Kawasaki, Sakiko Honda
Cureus
Cardiovascular Conditions and Treatments
article

Systolic Ejection Murmur in a Case of Patent Ductus Arteriosus and Pulmonary Hypertension With Liver Cirrhosis

Michiyo Yamano, Tatsuya Kawasaki, Sakiko Honda
article en

Abstract

Patent ductus arteriosus (PDA) is a congenital anomaly characterized by a persistent connection between the descending aorta and the pulmonary artery. While patients with PDA typically present with a continuous murmur, atypical cases, such as those with systolic murmurs or no murmurs (although the exact mechanism remains unclear), pose diagnostic challenges. We report a case of a 38-year-old woman with alcoholic liver cirrhosis, referred for liver transplantation, in whom a systolic ejection murmur prompted further evaluation. Diagnostic imaging and right heart catheterization confirmed PDA with mild pulmonary hypertension, without evidence of Eisenmenger physiology. This case underscores the importance of recognizing atypical murmur patterns in the diagnosis of PDA to avoid misdiagnosis or delayed diagnosis.

CureusVol. 17(3)
Matsushita Memorial Hospital (JP)
Good health and well-being
Openalex Percentile: Top 93%
Cardiovascular Conditions and Treatments
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