A rare case of a gliosarcoma tumour in a 14-year-old female teenager: a case report

Abstract Background Glioblastomas (GBMs) are the most common malignant primary brain tumours, accounting for a significant portion of brain tumour-related morbidity and mortality. However, it is more commonly seen in the male population and rarely occurs in paediatric cases. Also, when it occurs in paediatrics, the giant cell type has been shown to be the most common type amongst children. Our inex case is a female paediatric patient who was diagnosed with glioblastoma multiforme. Case presentation This was a case of a 14-year-old female teenager who presented on account of limping, inability to adduct the right digits to hold a pen and right-sided hemiparesis. First symptoms showed a week prior to presentation. Brain scan showed a left parietal mixed intensity space occupying lesion. A gross total tumour resection surgery was done and after 7 h, all neurological deficits were gone. An analysis of the tumour was done in the pathology laboratory and showed a gliosarcomatous glioblastoma multiforme tumour, on histology. Following surgery, patient has been doing so well. Conclusion Glioblastoma is very rare in paediatric patients; however, when it presents, it presents with varying characteristics. It is more common in males, although women have a higher survival rate. This may be linked to behavioural, hormonal, or genetic reason. GTR as against STR in GBM gives clinically and prognostically better outcomes. Finally, timely and precision surgeries are most vital to a good outcome.

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Publication Details

Journal
The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgery
Published
2025-03-17
DOI
https://doi.org/10.1186/s41984-025-00390-0
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

A rare case of a gliosarcoma tumour in a 14-year-old female teenager: a case report

Ega Otorkpa, Daniel David Otobo, Christopher Okpanachi, Joseph O. Obande et al.
The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgery
Glioma Diagnosis and Treatment
article

A rare case of a gliosarcoma tumour in a 14-year-old female teenager: a case report

Ega Otorkpa, Daniel David Otobo, Christopher Okpanachi, Joseph O. Obande, Stanley U. Lemchi, Yusuf Dawan, Adekola Olomo, Ejieke Elekwa, Stanley Orji, Geoffrey Ndu
article en

Abstract

Abstract Background Glioblastomas (GBMs) are the most common malignant primary brain tumours, accounting for a significant portion of brain tumour-related morbidity and mortality. However, it is more commonly seen in the male population and rarely occurs in paediatric cases. Also, when it occurs in paediatrics, the giant cell type has been shown to be the most common type amongst children. Our inex case is a female paediatric patient who was diagnosed with glioblastoma multiforme. Case presentation This was a case of a 14-year-old female teenager who presented on account of limping, inability to adduct the right digits to hold a pen and right-sided hemiparesis. First symptoms showed a week prior to presentation. Brain scan showed a left parietal mixed intensity space occupying lesion. A gross total tumour resection surgery was done and after 7 h, all neurological deficits were gone. An analysis of the tumour was done in the pathology laboratory and showed a gliosarcomatous glioblastoma multiforme tumour, on histology. Following surgery, patient has been doing so well. Conclusion Glioblastoma is very rare in paediatric patients; however, when it presents, it presents with varying characteristics. It is more common in males, although women have a higher survival rate. This may be linked to behavioural, hormonal, or genetic reason. GTR as against STR in GBM gives clinically and prognostically better outcomes. Finally, timely and precision surgeries are most vital to a good outcome.

The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgeryVol. 40(1)
American Academy of Neurology (US), African Field Epidemiology Network (NG), Operation PAR (US), University of Abuja Teaching Hospital (NG)
Openalex Percentile: Top 92%
Glioma Diagnosis and Treatment
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