A Novel Stability-Indicating HPLC Method with Kinetics Study for the Concurrent Analysis of Anti‐Hypertensive Drug Combination of Atenolol and Indapamide

The developed stability-indicating HPLC method successfully identified and quantified atenolol and indapamide in the presence of degradation products. It offered high specificity, precision, and robustness, making it ideal for routine pharmaceutical analysis. The method distinguished between the active drugs and degradation products under various stress conditions, ensuring the long-term stability and efficacy of atenolol and indapamide formulations. These findings can significantly contribute to pharmaceutical quality control, ensuring drugs' safety and effectiveness.