Has the pendulum swung too far? Discretionary single‐unit red blood cell transfusion in trauma is associated with infection, thromboembolic events, and mortality
Transfusion of a single unit of RBC within the first 4 h of arrival in trauma patients with no subsequent transfusion during hospitalization was associated with an increased risk of mortality, infection, and a thromboembolic event. When weighing the decision to transfuse trauma patients with equivocal signs of hemorrhage, one needs to balance the potential harm against the likelihood that such transfusion is necessary.
Authors
- Khaled Abdul Jawad (ORCID: https://orcid.org/0000-0001-9249-7154)
- Franklin Dexter (ORCID: https://orcid.org/0000-0001-5897-2484)
- D. Dante Yeh (ORCID: https://orcid.org/0000-0003-4994-0100)
- Richard H. Epstein (ORCID: https://orcid.org/0000-0001-8466-3845)
- Roman Dudaryk (ORCID: https://orcid.org/0000-0002-9704-7539)
- Michael D. Cobler-Lichter (ORCID: https://orcid.org/0000-0002-3864-0789)
Institutions
- University of Iowa (US)
- University of Miami (US)
- Denver Health Medical Center (US)
- University of Pittsburgh Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Transfusion
- Published
- 2025-03-16
- DOI
- https://doi.org/10.1111/trf.18191
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00