MRI monitoring of USPIO-labeled BMSCs combined with alginate scaffold for cartilage defect repair
This study demonstrated that BMSCs exhibit significant regenerative potential for cartilage defect repair. USPIO labeling enables non-invasive, dynamic monitoring of the repair process without adverse effects on cell viability or differentiation. These findings provide experimental evidence supporting the application of BMSCs combined with magnetic labeling technology in cartilage regeneration.
Authors
- Hui Zhen (ORCID: https://orcid.org/0000-0002-5856-3709)
- Meiling Qi (ORCID: https://orcid.org/0000-0003-4372-4597)
- Yuanyuan Jiao (ORCID: https://orcid.org/0009-0000-7192-2676)
- Xinyao Chen (ORCID: https://orcid.org/0000-0003-2421-1649)
- Jing Luo (ORCID: https://orcid.org/0000-0003-2702-120X)
- Juan Zhen (ORCID: https://orcid.org/0000-0002-6111-9692)
- Le Chang (ORCID: https://orcid.org/0000-0002-4509-9425)
- Xiaolong Bai (ORCID: https://orcid.org/0009-0002-7411-8485)
- Shao‐Chun Lu (ORCID: https://orcid.org/0000-0002-3297-1245)
- Zhenyu Liu (ORCID: https://orcid.org/0000-0002-2085-2628)
- Yingchao Wang (ORCID: https://orcid.org/0000-0003-3590-9233)
Institutions
- Shanxi Medical University (CN)
- Second Hospital of Shanxi Medical University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-03-17
- DOI
- https://doi.org/10.3389/fbioe.2025.1554292
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.67
Funders
- National Natural Science Foundation of China