<scp>SARS</scp> ‐ <scp>CoV</scp> ‐2 Entry Factors <scp> <i>ACE2</i> </scp> , <scp> <i>TMPRSS2</i> </scp> and <scp> <i>FURIN</i> </scp> in Salivary Glands From Primary Sjögren's Disease
Our analysis revealed a high expression of ACE2 in pSjD. ACE2, TMPRSS2, and FURIN mRNA levels are increased in pSjD in comparison to pleomorphic adenomas. Neither ACE2, TMPRSS2, nor furin was consistently associated with SARS-CoV-2 positivity in pSjD. These findings may guide future investigations on the effects of SARS-CoV-2 in a subset of salivary gland diseases.
Authors
- Débora Cerqueira Calderaro (ORCID: https://orcid.org/0000-0001-5535-3223)
- Sílvia Ferreira de Sousa (ORCID: https://orcid.org/0000-0001-7820-4749)
- Tarcı́lia Aparecida Silva (ORCID: https://orcid.org/0000-0001-9623-7835)
- Ricardo Santiago Gomez (ORCID: https://orcid.org/0000-0001-8770-8009)
- Marina Gonçalves Diniz (ORCID: https://orcid.org/0000-0002-4212-1172)
- Fernanda Aragão Felix (ORCID: https://orcid.org/0000-0003-3054-4642)
- Maurício Augusto Aquino de Castro (ORCID: https://orcid.org/0000-0001-6013-9344)
- Flávia Martins Vasconcelos Filiú (ORCID: https://orcid.org/0009-0004-4008-9182)
- Leandro Augusto Tanure
Institutions
- Universidade Federal de Minas Gerais (BR)
- Faculdade de Ciências Médicas de Minas Gerais (BR)
- Hospital das Clínicas da Universidade Federal de Minas Gerais (BR)
Publication Details
- Journal
- Journal of Oral Pathology and Medicine
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1111/jop.13621
- Citations
- 4
- Primary Topic
- Dermatological and COVID-19 studies
- Type
- article
- Field-Weighted Citation Impact
- 8.02
Funders
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais