Clear cell sarcoma of salivary gland: A case report

Malignant mesenchymal tumors of the salivary glands are neoplasms whose histopathological picture represents a very big diagnostic challenge. Most tumors of the parotid glands are benign, and for malignant neoplasms, immunohistochemistry is essential for diagnosis. The aim is to present a rare case of a mesenchymal malignant tumor of the parotid gland, including diagnostics and surgical therapy. A 67-year-old patient presented with a tumor around the parotid gland. Sonographically, the change resembled an adenoma, although the differential diagnosis did not exclude a pathological entity of another etiology. The patient underwent a superficial parotidectomy, and the operative and postoperative course was without complications. Immunohistochemical analysis in combine with histopath results confirmed the final diagnosis of Clear Cell Sarcoma of the parotid gland. Clear cell sarcoma of the parotid gland is a rare malignant neoplasm. Timely diagnosis and total parotidectomy with negative resection margins, in the first year after the operation ensure a satisfactory postoperative result without recurrence and meta-changes. Doctors should be very cautious in such situations because the histopathological examination with immunohistochemical analysis gives a clear picture of the tumor in question as a differential diagnosis.

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Publication Details

Journal
Current Problems in Cancer Case Reports
Published
2025-03-17
DOI
https://doi.org/10.1016/j.cpccr.2025.100359
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Clear cell sarcoma of salivary gland: A case report

Slobodan Tabaković, Saša Tabaković
Current Problems in Cancer Case Reports
Salivary Gland Tumors Diagnosis and Treatment
article

Clear cell sarcoma of salivary gland: A case report

Slobodan Tabaković, Saša Tabaković
article en

Abstract

Malignant mesenchymal tumors of the salivary glands are neoplasms whose histopathological picture represents a very big diagnostic challenge. Most tumors of the parotid glands are benign, and for malignant neoplasms, immunohistochemistry is essential for diagnosis. The aim is to present a rare case of a mesenchymal malignant tumor of the parotid gland, including diagnostics and surgical therapy. A 67-year-old patient presented with a tumor around the parotid gland. Sonographically, the change resembled an adenoma, although the differential diagnosis did not exclude a pathological entity of another etiology. The patient underwent a superficial parotidectomy, and the operative and postoperative course was without complications. Immunohistochemical analysis in combine with histopath results confirmed the final diagnosis of Clear Cell Sarcoma of the parotid gland. Clear cell sarcoma of the parotid gland is a rare malignant neoplasm. Timely diagnosis and total parotidectomy with negative resection margins, in the first year after the operation ensure a satisfactory postoperative result without recurrence and meta-changes. Doctors should be very cautious in such situations because the histopathological examination with immunohistochemical analysis gives a clear picture of the tumor in question as a differential diagnosis.

Current Problems in Cancer Case ReportsVol. 18
Centar za Promociju Nauke (RS), University of Prishtina (XK)
Zero hunger
Openalex Percentile: Top 92%
Salivary Gland Tumors Diagnosis and Treatment
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