Inorganic salts of topiroxostat: metastable tautomeric form and improved pharmaceutical performance
Topiroxostat monotonically exists in the 2 H -tautomeric form in all polymorphic structures, while it exists in the protonated 3 H -tautomeric form after salt formation.
Authors
- Ting Jiao (ORCID: https://orcid.org/0000-0001-7670-1581)
- Lin Wang (ORCID: https://orcid.org/0000-0002-7828-1071)
- Zongwu Deng (ORCID: https://orcid.org/0000-0002-9564-3740)
- Hailu Zhang
- Jiangying Li
- Xiaoju Shi (ORCID: https://orcid.org/0009-0001-5917-7674)
- Xiaojuan Wang (ORCID: https://orcid.org/0000-0002-8344-4373)
- Haowen Ma
- Mao-Wu Nie (ORCID: https://orcid.org/0000-0001-8130-4986)
Institutions
- University of Science and Technology of China (CN)
- Chinese Academy of Sciences (CN)
- Suzhou Institute of Nano-tech and Nano-bionics (CN)
- Chuzhou University (CN)
- Suzhou Vocational Health College (CN)
- Wuhan University of Science and Technology (CN)
- Wuhan Institute of Technology (CN)
Publication Details
- Journal
- CrystEngComm
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ce00073d
- Primary Topic
- Organometallic Compounds Synthesis and Characterization
- Type
- article
- Field-Weighted Citation Impact
- 0.00