Perioperative and oncologic outcomes after total pancreatectomy and pancreatoduodenectomy for pancreatic head adenocarcinoma—A propensity score–matched analysis from the German Cancer Registry Group
The results of this study show greater perioperative morbidity and mortality after total pancreatectomy compared with pancreatoduodenectomy for pancreatic head malignancy. Also, long-term survival was worse after total pancreatectomy. These results emphasize the role of pancreatoduodenectomy as a standard surgical procedure for pancreatic head adenocarcinoma and suggest that total pancreatectomy should only be performed in selected patients.
Authors
- Tobias Keck (ORCID: https://orcid.org/0000-0001-7651-6183)
- Kim C. Honselmann (ORCID: https://orcid.org/0000-0002-5699-2286)
- Andrea Sackmann
- Thaer S. A. Abdalla (ORCID: https://orcid.org/0000-0002-0448-2225)
- Ulrich F. Wellner (ORCID: https://orcid.org/0000-0002-8632-166X)
- Stanislav Litkevych
- Fabian Reinwald
- Barbara Franke (ORCID: https://orcid.org/0000-0003-4375-6572)
- Kees Kleihues-van Tol (ORCID: https://orcid.org/0000-0002-0491-2248)
- Steffen Deichmann (ORCID: https://orcid.org/0000-0002-4985-4723)
- Sylke Ruth Zeißig (ORCID: https://orcid.org/0000-0002-0743-6128)
- Markus Kist (ORCID: https://orcid.org/0000-0003-2683-5842)
- Lennart von Fritsch (ORCID: https://orcid.org/0000-0002-5296-6355)
- Rüdiger Braun (ORCID: https://orcid.org/0000-0002-1662-2109)
- Jannis Duhn
- Louisa Bolm (ORCID: https://orcid.org/0000-0002-1612-1857)
- Monika Klinkhammer‐Schalke (ORCID: https://orcid.org/0000-0001-5066-2051)
- Bernd Holleczek
- Anna Krauß (ORCID: https://orcid.org/0009-0001-6851-6172)
Institutions
- German Cancer Research Center (DE)
- Universitätsmedizin Greifswald (DE)
- Universitäres Kinderwunschzentrum Lübeck (DE)
- German Cancer Society (DE)
- University Hospital Schleswig-Holstein (DE)
- Hessian Agency for Nature Conservation, Environment and Geology (DE)
- Krebsregister Saarland (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Surgery
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1016/j.surg.2025.109292
- Citations
- 2
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09