The Clinicopathologic Pattern of Prostate Cancer at a Tertiary Care Teaching Hospital in Bangladesh

Objectives: The objective of this study was to determine the clinicopathologic pattern of prostatic diseases. To determine the Gleason grading and scoring of prostate cancer in Bangladesh. Methods: The records of patients who underwent histopathological examinations of prostatic biopsy specimens were reviewed retrospectively at National Institute of Kidney Diseases and Urology in Bangladesh during the period of January 2022 to December 2023. The histological diagnosis prostatic diseases and Gleason grading and scoring of the biopsy specimens of prostate cancer patients were studied. Results: A total of 220 patients were included in this study. The age ranged from 45-100 years (median age: 58 years). One hundred and sixty cases of transurethral resection of the prostate (TURP), 40 cases of digital guided transrectal core biopsy specimens, 10 cases of transrectal ultrasound (TRUS) guided core biopsy specimens, 08 cases of simple prostatectomies and 02 cases of radical prostatectomies were studied. The most frequent disease of this study group were benign hyperplasia prostate (67.27%, n=220) followed by adenocarcinoma of prostate in 60 cases (27.27%, n=220). Out of 220 total cases of prostatic biopsy, 160 (72.27%, n=220) cases were prostatic diseases and rest 60 (27.27%, n=220) prostate cancer. Diagnostic sensitivity of TRUS guided biopsy specimens (80%, n=10) were more than digital guided core biopsy specimens (62.5%, n=40). Fourteen cases (8.75%, n=148) of TURP obtained biopsy showed prostate cancer. Out of 8 cases of total prostatectomy obtained biopsy, 07(87.5%) cases were. Rest one (12.5%) was benign hyperplasia prostate. All of the two radical prostatectomy specimens obtained prostatic tissue showed poorly differentiated adenocarcinoma prostate. Out of 8 cases of total prostatectomy obtained biopsy, 07(87.5%) cases were adenocarcinoma prostate. Rest one (12.5%) was benign hyperplasia prostate. All radical prostatectomy obtained prostatic tissue showed poorly diff