o8G-modified circPLCE1 inhibits lung cancer progression via chaperone-mediated autophagy
o8G-modified circPLCE1 inhibits lung cancer progression through CMA to inhibit macroautophagy and alter cell fate. This study provides not only a new theoretical basis for elucidating the molecular mechanism of lung cancer progression but also potential targets for lung cancer treatment.
Authors
- Aruo Nan (ORCID: https://orcid.org/0000-0003-0351-8561)
- Sixian Chen
- Xiaodong Zhou (ORCID: https://orcid.org/0000-0001-8198-5902)
- Wenyi Peng (ORCID: https://orcid.org/0000-0001-7699-6850)
- Deqing Li
- Haotian Xu (ORCID: https://orcid.org/0000-0003-1673-6779)
- Yihong Gao (ORCID: https://orcid.org/0000-0002-9293-4075)
- Xingcai Chen (ORCID: https://orcid.org/0000-0002-9489-5014)
- Gang Li (ORCID: https://orcid.org/0000-0003-3184-1032)
- Ruirui Zhang (ORCID: https://orcid.org/0000-0002-5372-389X)
- Jiaxi Wu
- Qingyun Zhao
- Shengyi Yuan
- Dunyu Cai
Institutions
- Guangxi Medical University (CN)
Publication Details
- Journal
- Molecular Cancer
- Published
- 2025-03-17
- DOI
- https://doi.org/10.1186/s12943-025-02283-0
- Citations
- 7
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- National Natural Science Foundation of China