Cognitive and Motor profiles of Preterm Infants with Hypoxic Ischemic Encephalopathy (HIE): A Case Report

Hypoxic Ischemic Encephalopathy (HIE) significantly impacts infants' cognitive and motor development, necessitating tailored evaluation tools for early identification and intervention. To address this need, this study aimed to build new normative data for the Bayley Scales of Infant and Toddler DevelopmentTM, Fourth Edition (BayleyTM-4), specific to HIE. A cross-sectional analysis of 54 infants across three age groups (6, 12, and 18 months), consisting of 18 each, revealed significant deficits in the cognitive and motor domains compared with those of matched controls. These findings highlight the need for HIE-specific benchmarks to improve diagnostic accuracy and inform targeted interventions. Establishing these norms can enable clinicians to design personalized strategies to enhance developmental outcomes.