Centrifugation Liver Support Using Regional Mesylate Anticoagulation is Safe for Liver Failure Patients with High Risk of Bleeding

Patients with acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) are at high risk of bleeding with traditional artificial liver support systems. To address the bleeding risk in liver failure patients, the safety of regional mesylate anticoagulation (RMA) in centrifugation artificial liver support systems (cALSS) is proposed for study.

Authors

Publication Details

Journal
Journal of Clinical and Translational Pathology
Published
2025-03-17
DOI
https://doi.org/10.14218/jctp.2024.00036
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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Centrifugation Liver Support Using Regional Mesylate Anticoagulation is Safe for Liver Failure Patients with High Risk of Bleeding

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Journal of Clinical and Translational Pathology
Liver Disease Diagnosis and Treatment
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Centrifugation Liver Support Using Regional Mesylate Anticoagulation is Safe for Liver Failure Patients with High Risk of Bleeding

Fei Sun, Xinfang Zhu, Jianming Zheng, Quanbao Zhang, Qi Zhang, Bo Wang, Rong Xia, Ruidong Li, Hong-Yuan Xue
article en

Abstract

Patients with acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) are at high risk of bleeding with traditional artificial liver support systems. To address the bleeding risk in liver failure patients, the safety of regional mesylate anticoagulation (RMA) in centrifugation artificial liver support systems (cALSS) is proposed for study.

Journal of Clinical and Translational PathologyVol. 000(000)
National Natural Science Foundation of China, National Key Research and Development Program of China
Zero hunger
Openalex Percentile: Top 92%
Liver Disease Diagnosis and Treatment
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