Anti-LGI1 autoimmune limbic encephalitis presenting with psychiatric manifestations – An under-recognized entity: A rare case report

Leucin-rich glioma-inactivated protein 1 (LGI1) encephalitis is the second most common cause of autoimmune encephalitis; it is a rare and poorly recognized phenomenon. Unlike the typical presentation of LGI1 type of limbic encephalitis in regard to age (30–70 years) as well as gender (M>F), we are describing a case of an adolescent female who presented to us with psychiatric manifestations and initial insignificant neuro-imaging, which led to misdiagnosis and thus delay in her treatment. This case study highlights how the clinician must think ahead of the prevalence patterns and entertain rare possibilities in such atypical cases.

Authors

Institutions

Publication Details

Journal
Archives of Biological Psychiatry
Published
2025-03-15
DOI
https://doi.org/10.25259/abp_7_2024
Citations
1
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
1.39
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Anti-LGI1 autoimmune limbic encephalitis presenting with psychiatric manifestations – An under-recognized entity: A rare case report

Navkiran Sooch Mahajan, Kshitija N. Mahajan, Ranjive Mahajan, Cherry Sikka
1 citations
Archives of Biological Psychiatry
Autoimmune Neurological Disorders and Treatments
1.39
article

Anti-LGI1 autoimmune limbic encephalitis presenting with psychiatric manifestations – An under-recognized entity: A rare case report

Navkiran Sooch Mahajan, Kshitija N. Mahajan, Ranjive Mahajan, Cherry Sikka
article en
1 citations

Abstract

Leucin-rich glioma-inactivated protein 1 (LGI1) encephalitis is the second most common cause of autoimmune encephalitis; it is a rare and poorly recognized phenomenon. Unlike the typical presentation of LGI1 type of limbic encephalitis in regard to age (30–70 years) as well as gender (M>F), we are describing a case of an adolescent female who presented to us with psychiatric manifestations and initial insignificant neuro-imaging, which led to misdiagnosis and thus delay in her treatment. This case study highlights how the clinician must think ahead of the prevalence patterns and entertain rare possibilities in such atypical cases.

Archives of Biological PsychiatryVol. 2
Dayanand Medical College & Hospital (IN)
Openalex Percentile: Top 22%
Autoimmune Neurological Disorders and Treatments
1.39
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.