How I treat thrombotic thrombocytopenic purpura

Introduction . Thrombotic thrombocytopenic purpura (TTP) is a rare disease manifested by non-immune thrombocytopenia, microangiopathic hemolytic anemia and organ and system dysfunction. Aim : to present the scheme of treatment of a patient with TTP. Main findings . The case report of a 32-years-old patient, in whom TTP manifested with anemia, thrombocytopenia, and ischemic stroke, is presented. The patient was successfully treated with plasma exchange, prednisolone, caplacizumab, rituximab. Diagnostic errors, logic of prescription and cancellation of these or those drugs are discussed.