Unmasking the Silent Threat: Prevalence of Cardiovascular Risk Factors in MS Patients in Bucharest, Romania
<b>Background and Objectives:</b> This study aims to identify cardiovascular risk factors among 91 patients with multiple sclerosis in Bucharest, Romania, using data from medical records and a self-administered questionnaire. <b>Materials and Methods:</b> The research focuses on smoking status, body mass index, blood sugar, cholesterol, triglycerides, blood pressure, and renal function. The average age of the patients was 42.90 ± 10.60 years, and 74.73% were female. The average BMI was 23.89 kg/m<sup>2</sup> ± 4.74 kg/m<sup>2</sup> (lower than in the general population), with 41.76% of patients having a BMI outside normal limits. The majority were former smokers (35.87%), followed by non-smokers (28.26%), and the fewest were smokers of more than 20 cigarettes/day (7.61%). The average total cholesterol was 198.48 ± 38.56 mg/dL, triglycerides were 114.22 mg/dL ± 76.2281 mg/dL, and blood glucose was 97.54 ± 36.58 mg/dL. While 25.27% of the patients had fasting blood glucose > 126 mg/dL, only five patients were diagnosed with DM. The average blood pressure was 137.5165 ± 19.5047 mmHg, with only 11 patients diagnosed with HTA. <b>Results:</b> The study found an average cardiovascular risk of 6.6133% ± 7.1412%, with higher values among males, rural patients, those with secondary-progressive MS, and those with a disease progression >10 years (after age adjustment). <b>Conclusions:</b> The study underscores the importance of identifying and combating cardiovascular risk factors in patients with multiple sclerosis.
Authors
- Octavian Vasiliu (ORCID: https://orcid.org/0000-0001-6345-3478)
- Monica Marilena Ţânţu (ORCID: https://orcid.org/0000-0002-1038-7953)
- Carmen Adella Sîrbu (ORCID: https://orcid.org/0000-0002-1982-1066)
- C Pleşa (ORCID: https://orcid.org/0000-0003-2048-5431)
- Adrian Badea (ORCID: https://orcid.org/0000-0002-5875-1806)
- Săndica Bucurica (ORCID: https://orcid.org/0000-0002-8787-3829)
- Alice Elena Munteanu (ORCID: https://orcid.org/0000-0002-6122-7781)
- Daniela Anghel
- Andreea Pleșa
- Elena Andreea Arsene
Institutions
- Titu Maiorescu University (RO)
- Carol Davila University of Medicine and Pharmacy (RO)
- University of Pitesti (RO)
- Clinical Emergency Hospital Bucharest (RO)
- Academia Oamenilor de Știință din România (RO)
- Universitatea Națională de Știință și Tehnologie Politehnica București (RO)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2025-03-15
- DOI
- https://doi.org/10.3390/jcm14062001
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00