Unmasking the Silent Threat: Prevalence of Cardiovascular Risk Factors in MS Patients in Bucharest, Romania

<b>Background and Objectives:</b> This study aims to identify cardiovascular risk factors among 91 patients with multiple sclerosis in Bucharest, Romania, using data from medical records and a self-administered questionnaire. <b>Materials and Methods:</b> The research focuses on smoking status, body mass index, blood sugar, cholesterol, triglycerides, blood pressure, and renal function. The average age of the patients was 42.90 ± 10.60 years, and 74.73% were female. The average BMI was 23.89 kg/m<sup>2</sup> ± 4.74 kg/m<sup>2</sup> (lower than in the general population), with 41.76% of patients having a BMI outside normal limits. The majority were former smokers (35.87%), followed by non-smokers (28.26%), and the fewest were smokers of more than 20 cigarettes/day (7.61%). The average total cholesterol was 198.48 ± 38.56 mg/dL, triglycerides were 114.22 mg/dL ± 76.2281 mg/dL, and blood glucose was 97.54 ± 36.58 mg/dL. While 25.27% of the patients had fasting blood glucose > 126 mg/dL, only five patients were diagnosed with DM. The average blood pressure was 137.5165 ± 19.5047 mmHg, with only 11 patients diagnosed with HTA. <b>Results:</b> The study found an average cardiovascular risk of 6.6133% ± 7.1412%, with higher values among males, rural patients, those with secondary-progressive MS, and those with a disease progression >10 years (after age adjustment). <b>Conclusions:</b> The study underscores the importance of identifying and combating cardiovascular risk factors in patients with multiple sclerosis.

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Journal
Journal of Clinical Medicine
Published
2025-03-15
DOI
https://doi.org/10.3390/jcm14062001
Primary Topic
Multiple Sclerosis Research Studies
Type
article
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article

Unmasking the Silent Threat: Prevalence of Cardiovascular Risk Factors in MS Patients in Bucharest, Romania

Octavian Vasiliu, Monica Marilena Ţânţu, Carmen Adella Sîrbu, C Pleşa et al.
Journal of Clinical Medicine
Multiple Sclerosis Research Studies
article

Unmasking the Silent Threat: Prevalence of Cardiovascular Risk Factors in MS Patients in Bucharest, Romania

Octavian Vasiliu, Monica Marilena Ţânţu, Carmen Adella Sîrbu, C Pleşa, Adrian Badea, Săndica Bucurica, Alice Elena Munteanu, Daniela Anghel, Andreea Pleșa, Elena Andreea Arsene
article en

Abstract

<b>Background and Objectives:</b> This study aims to identify cardiovascular risk factors among 91 patients with multiple sclerosis in Bucharest, Romania, using data from medical records and a self-administered questionnaire. <b>Materials and Methods:</b> The research focuses on smoking status, body mass index, blood sugar, cholesterol, triglycerides, blood pressure, and renal function. The average age of the patients was 42.90 ± 10.60 years, and 74.73% were female. The average BMI was 23.89 kg/m<sup>2</sup> ± 4.74 kg/m<sup>2</sup> (lower than in the general population), with 41.76% of patients having a BMI outside normal limits. The majority were former smokers (35.87%), followed by non-smokers (28.26%), and the fewest were smokers of more than 20 cigarettes/day (7.61%). The average total cholesterol was 198.48 ± 38.56 mg/dL, triglycerides were 114.22 mg/dL ± 76.2281 mg/dL, and blood glucose was 97.54 ± 36.58 mg/dL. While 25.27% of the patients had fasting blood glucose > 126 mg/dL, only five patients were diagnosed with DM. The average blood pressure was 137.5165 ± 19.5047 mmHg, with only 11 patients diagnosed with HTA. <b>Results:</b> The study found an average cardiovascular risk of 6.6133% ± 7.1412%, with higher values among males, rural patients, those with secondary-progressive MS, and those with a disease progression >10 years (after age adjustment). <b>Conclusions:</b> The study underscores the importance of identifying and combating cardiovascular risk factors in patients with multiple sclerosis.

Journal of Clinical MedicineVol. 14(6)
Titu Maiorescu University (RO), Carol Davila University of Medicine and Pharmacy (RO), University of Pitesti (RO), Clinical Emergency Hospital Bucharest (RO), Academia Oamenilor de Știință din România (RO), Universitatea Națională de Știință și Tehnologie Politehnica București (RO)
Good health and well-being
Openalex Percentile: Top 93%
Multiple Sclerosis Research Studies
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