P581: Customized “clinical interpretive reports” of genomic sequencing results for non-genetics providers in safety-net neonatal intensive care units: Development and implementation

Rapid genomic sequencing (rGS) has high diagnostic and clinical utility in Neonatal Intensive Care Units (NICUs). However, safety-net NICUs that disproportionately serve marginalized populations face barriers that limit access to rGS, including limited genetics expertise, high cost, and complicated logistics. The Virtual Genome Center (VIGOR) study is an implementation study that aims to address these barriers by providing rGS in safety-net NICUs using an innovative virtual delivery model. In the VIGOR study, neonatal providers with often limited genetics expertise who work in safety-net NICUs disclose rGS results to families.