P407: Atypical reactions to infantile spasms medications in a child with UNC80 deficiency

During her initial hospital admission, clobazam and levetiracetam were started. ACTH therapy was started but was discontinued due to adverse events. As an outpatient, she was prescribed vigabatrin; however, due to side effects and poor clinical response, it was discontinued. She then started valproate and zonisamide. After transitioning to a new hospital, ACTH therapy was reattempted and clobazam was increased.

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Publication Details

Journal
Genetics in Medicine Open
Published
2025-01-01
DOI
https://doi.org/10.1016/j.gimo.2025.103274
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

P407: Atypical reactions to infantile spasms medications in a child with UNC80 deficiency

David Neil Toupin, Kelly Kremer, Howard Burdette Huffman
Genetics in Medicine Open
Cardiac Arrhythmias and Treatments
article

P407: Atypical reactions to infantile spasms medications in a child with UNC80 deficiency

David Neil Toupin, Kelly Kremer, Howard Burdette Huffman
article en

Abstract

During her initial hospital admission, clobazam and levetiracetam were started. ACTH therapy was started but was discontinued due to adverse events. As an outpatient, she was prescribed vigabatrin; however, due to side effects and poor clinical response, it was discontinued. She then started valproate and zonisamide. After transitioning to a new hospital, ACTH therapy was reattempted and clobazam was increased.

Genetics in Medicine OpenVol. 3
University of Kentucky (US), University of Cincinnati (US)
Openalex Percentile: Top 92%
Cardiac Arrhythmias and Treatments
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