Exploration of Conserved Human Adipose Subpopulations Using Targeted Single‐Nuclei RNA Sequencing Data Sets

Human adipose cell populations are distinct from mice, and the pericyte subpopulation in human adipose tissues are present across adipose depots. Given that vascular mural cells, including pericytes and smooth-muscle cells, can undergo adipogenesis, we postulate that they are a novel source of adipocytes in the vascular microenvironment.

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Publication Details

Journal
Journal of the American Heart Association
Published
2025-03-17
DOI
https://doi.org/10.1161/jaha.124.038465
Citations
3
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
2.42
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article

Exploration of Conserved Human Adipose Subpopulations Using Targeted Single‐Nuclei RNA Sequencing Data Sets

Lucy Liaw, Kimberly T. Malka, Matthew D. Lynes, Christian M. Potts et al.
3 citations
Journal of the American Heart Association
Single-cell and spatial transcriptomics
2.42
article

Exploration of Conserved Human Adipose Subpopulations Using Targeted Single‐Nuclei RNA Sequencing Data Sets

Lucy Liaw, Kimberly T. Malka, Matthew D. Lynes, Christian M. Potts, Xuehui Yang
article en
3 citations

Abstract

Human adipose cell populations are distinct from mice, and the pericyte subpopulation in human adipose tissues are present across adipose depots. Given that vascular mural cells, including pericytes and smooth-muscle cells, can undergo adipogenesis, we postulate that they are a novel source of adipocytes in the vascular microenvironment.

Journal of the American Heart AssociationVol. 14(6)
MaineHealth (US)
Life in Land
Openalex Percentile: Top 13%
Single-cell and spatial transcriptomics
2.42
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