Delirium is a Potential Predictor of Unfavorable Long-term Functional Outcomes in Patients with Acute Ischemic Stroke: A Prospective Observational Study
PSD is a strong independent predictor of poor 3-month outcomes in AIS, including higher mortality and disability. Our findings highlight the critical role of inflammation and coagulation dysfunction in the pathogenesis of PSD. Furthermore, we present the clinical utility of a predictive model integrating delirium and relevant biomarkers to assess the risk of adverse outcomes at 3 months, suggesting potential targets for intervention.
Authors
- Luqian Zhan
- Yujie Tu
- Fangyi Xiao (ORCID: https://orcid.org/0000-0003-4579-9066)
- Heyu Zhang (ORCID: https://orcid.org/0000-0002-4461-2290)
- Yisi Lin
- Chenhui Lin
- Yanyan Chen (ORCID: https://orcid.org/0000-0001-7882-7874)
- Yanwei Li (ORCID: https://orcid.org/0009-0008-1675-0283)
- Chenglong Xie (ORCID: https://orcid.org/0000-0002-1132-0179)
- Yaoyao Lin
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Wenzhou Hospital of Traditional Chinese Medicine (CN)
- Shaoxing People's Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/jir.s505038
- Citations
- 4
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.18
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province