The Oncogenic Role of <scp>UBXN1</scp> in Gastric Cancer Is Attributed to the <scp>METTL16</scp>‐Mediated <scp>m6A</scp> Methylation and Histone Modifications
Our findings demonstrate the spatio-temporal regulation of UBXN1 expression in GC cells by METTL16 through a combination of transcriptional and post-transcriptional mechanisms. The synergistic interplay of these various epigenetic mechanisms provides new prospects for tumor diagnosis and precision treatment.
Authors
- Tianpeng Gao (ORCID: https://orcid.org/0000-0001-6821-3836)
- Yuan Wu (ORCID: https://orcid.org/0000-0002-9445-7938)
- Kesong Shi
- Hua Guo
- Yani Chen
- Xinyao Fu
- Haiquan Yu
Institutions
- Inner Mongolia University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/cam4.70772
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China